-
Potential role of ANGPTL4 in cancer progression, metastasis, and metabolism: a brief review
Role of ANGPTL4 in cancer metastasis. ANGPTL4 plays a crucial role in various aspects of cancer metastasis. It promotes the growth of new blood vessels, which is pivotal to tumor nutrition and spread. It also influences cancer metastasis by impacting EMT and signaling pathways. Within the tumor microenvironment (TME), ANGPTL4 interacts with CAF, TAM, T-cell, and secretes MMP- and -9, influencing ECM remodeling, metastatic process, lymph node metastasis, and perineural invasion. flANGPTL4 and cANGPTL4 typically promote tumor growth and lung metastasis, whereas nANGPTL4 inhibits metastasis by reducing vascularity at metastatic sites. -
Challenges and innovations in hematopoietic stem cell transplantation: exploring bone marrow niches and new model systems
Hematopoietic niches in bone marrow. Organization and cellular interactions within the hematopoietic stem cell (HSC) niches of adult bone marrow (BM). HSCs are predominantly situated in proximity to the marrow vasculature, in perivascular niches. The niche includes various cell types, such as endothelial cells, CD169+ macrophages, and LepR+ CXCL12-abundant reticular (CAR) cells, dendritic cells (DCs), Nestin+ bone marrow stromal cells (BMSCs), and adipocytes. The niche contributes to HSC self-renewal, proliferation, and differentiation via the expression of CXCL12 and stem cell factor (SCF). Conversely, the endosteal niche houses quiescent HSCs, and is characterized by osteoblast, osteocyte, osteoclast, osteomac, and schwann cells, and megakaryocytes, which provide a specialized cellular architecture for hematopoiesis regulation and quiescence. The factors related to bone metabolisms and transforming growth factor beta-1 (TGF-β1), play a crucial role in the long-term persistence of quiescent HSCs. Various factors in the microenvironment, such as stiffness, calcium levels, oxygen gradients, and reactive oxygen species, help maintain the dormancy and quiescence of HSCs.
- Current Issue
- Perspectives
- Minireviews
- Online First
- Most Read
Online First
- Online First articles have been peer reviewed, accepted for publication and published online; they have not yet been assigned to a journal issue. When these articles are published in an issue, they will be removed from this page.
- Online First articles are copy-edited, typeset and approved by the authors before publication.
BMB Reports 2024; 57(8): 343~380
Top 10 cited articles
Top 10 cited articles
No.
Cited items
Category
Citations
1
Sirtuin signaling in cellular senescence and aging
Shin-Hae Lee, Ji-Hyeon Lee, Hye-Yeon Lee & Kyung-Jin Min.
BMB Reports. 2019 Jan; 52(1): 24-34. Invited Mini Review 298
Shin-Hae Lee, Ji-Hyeon Lee, Hye-Yeon Lee & Kyung-Jin Min.
BMB Reports. 2019 Jan; 52(1): 24-34. Invited Mini Review 298
2
Cancer stem cell heterogeneity: origin and new perspectives on CSC targeting
Kiyoung Eun, Seok Won Ham, and Hyunggee Kim.
BMB Reports. 2017 Mar; 50(3): 117-125. Invited Mini Review 249
Kiyoung Eun, Seok Won Ham, and Hyunggee Kim.
BMB Reports. 2017 Mar; 50(3): 117-125. Invited Mini Review 249
3
Cancer stem cell surface markers on normal stem cells
Won-Tae Kim, and Chun Jeih Ryu.
BMB Reports. 2017 Jun; 50(6): 285-298. Invited Mini Review 232
Won-Tae Kim, and Chun Jeih Ryu.
BMB Reports. 2017 Jun; 50(6): 285-298. Invited Mini Review 232
4
Highlighted STAT3 as a potential drug target for cancer therapy
Haeri Lee, Ae Jin Jeong & Sang-Kyu Ye.
BMB Reports. 2019 Jul; 52(7): 415-423. Invited Mini Review 210
Haeri Lee, Ae Jin Jeong & Sang-Kyu Ye.
BMB Reports. 2019 Jul; 52(7): 415-423. Invited Mini Review 210
5
Sex as an important biological variable in biomedical research
Suk Kyeong Lee.
BMB Reports. 2018 Apr; 51(4): 167-173. Invited Mini Review 156
Suk Kyeong Lee.
BMB Reports. 2018 Apr; 51(4): 167-173. Invited Mini Review 156
6
Emerging role of mitophagy in human diseases and physiology
Jee-Hyun Um, and Jeanho Yun.
BMB Reports. 2017 Jun; 50(6): 299-307. Invited Mini Review 142
Jee-Hyun Um, and Jeanho Yun.
BMB Reports. 2017 Jun; 50(6): 299-307. Invited Mini Review 142
7
Senotherapeutics: emerging strategy for healthy aging and age-related disease
Eok-Cheon Kim & Jae-Ryong Kim.
BMB Reports. 2019 Jan; 52(1): 47-55. Invited Mini Review 136
Eok-Cheon Kim & Jae-Ryong Kim.
BMB Reports. 2019 Jan; 52(1): 47-55. Invited Mini Review 136
8
Metabolic influence on macrophage polarization and pathogenesis
Bikash Thapa & Keunwook Lee.
BMB Reports. 2019 Jun; 52(6): 360-372. Invited Mini Review 129
Bikash Thapa & Keunwook Lee.
BMB Reports. 2019 Jun; 52(6): 360-372. Invited Mini Review 129
9
Cancer stem cell metabolism: target for cancer therapy
Young Chan Chae, and Jae Ho Kim.
BMB Reports. 2018 Jul; 51(7): 319-326. Invited Mini Review 124
Young Chan Chae, and Jae Ho Kim.
BMB Reports. 2018 Jul; 51(7): 319-326. Invited Mini Review 124
10
Peripheral inflammatory biomarkers in Alzheimer’s disease: a brief review
Jong-Chan Park, Sun-Ho Han & Inhee Mook-Jung*.
BMB Reports. 2020 Jan; 53(1): 10-19. Invited Mini Review 122
Jong-Chan Park, Sun-Ho Han & Inhee Mook-Jung*.
BMB Reports. 2020 Jan; 53(1): 10-19. Invited Mini Review 122
Search for
-
Current Issue
August 2024
Volume 57
Issue 8
2023 SCI Impact Factor 2.9
BIOCHEMISTRY & MOLECULAR BIOLOGY 178/313