ELM - instance LIG_WH1 in sequence Q8TF74 at position 397

ELM
The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_WH1

o Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002696 Q8TF74 WIPF2
WIPF2_HUMAN
397 407 LDDFESKYSFHPVEDFPAPE TP --- Homo sapiens (Human) 440

o Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Zettl,2002 support likely FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Zettl,2002 support likely InteractionDetection

o Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O08816) WASL_RAT PF00568 (WH1)
WH1 domain
28 135 [mitab] [xml]

o Pathways

KEGG: The sequence Q8TF74 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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