ELM - instance LIG_SH2_GRB2like in sequence P09619 at position 716

ELM
The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_SH2_GRB2like

o Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000814 P09619 PDGFRB
PGFRB_HUMAN
716 719 RRPPSAELYSNALPVGLPLP TP --- Homo sapiens (Human) 1106

o Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Yokote,1996 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Yokote,1996 support certain FeatureDetection
experimental MI:0113 western blot in vitro Yokote,1996 support certain ParticipantIdentification FeatureDetection
not annotated not specified Yokote,1996 not specified not specified

o Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q14451) GRB7_HUMAN PF00017 (SH2)
SH2 domain
431 512 [mitab] [xml]

o Pathways

KEGG: The sequence P09619 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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