ELM - instance LIG_NRP_CendR_1 in sequence P49767 at position 226

ELM
The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_NRP_CendR_1

o Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004005 P49767 VEGFC
VEGFC_HUMAN
226 227 SCRCMSKLDVYRQVHSIIRR TP --- Homo sapiens (Human) 227

o Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Parker,2015 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Parker,2015 support certain InteractionDetection FeatureDetection
experimental MI:1311 differential scanning calorimetry Parker,2015 support certain InteractionDetection

o Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O60462) NRP2_HUMAN PF00754 (F5_F8_type_C)
F5/8 type C domain
292 424 128.0/270.0 [mitab] [xml]

o Pathways

KEGG: The sequence P49767 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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