ELM - instance LIG_NRBOX in sequence P48552 at position 818

ELM

The Eukaryotic Linear Motif resource for

Functional Sites in Proteins

o Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI000779	P48552 NRIP1 NRIP1_HUMAN	818	824	SFSKNGLLSRLLRQNQDSYL	TP	---	Homo sapiens (Human)	1158

o Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0018	two hybrid	in vivo	Heery,1997	support	certain	InteractionDetection
not annotated	not specified	not specified	not specified

o Switches

This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

SWTI000258:
ELM Switch SWTI000258
Binding of the 50114" target="_blank">estrogen ligand to the nuclear Estrogen receptor (ESR1) makes the binding site for the NRBOX motif of Nuclear receptor-interacting protein 1 (NRIP1) accessible.

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement