ELM - instance CLV_C14_Caspase3-7 in sequence Q13177 at position 209

ELM
The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
CLV_C14_Caspase3-7

o Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001918 Q13177 PAK2
PAK2_HUMAN
209 213 VPAPVGDSHVDGAAKSLDKQ TP --- Homo sapiens (Human) 524

o Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0113 western blot in vitro Rudel,1997 support likely ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Rudel,1997 support likely FeatureDetection
experimental MI:0194 cleavage reaction in vivo/in vitro Rudel,1997 support likely InteractionDetection

o Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P42574) CASP3_HUMAN PF00656 (Peptidase_C14)
Caspase domain
45 275 [mitab] [xml]

o Pathways

KEGG: The sequence Q13177 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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