Analysis of Sex Differences in Omics Data for Complex Diseases [R package XYomics version 0.1.1]

XYomics: Analysis of Sex Differences in Omics Data for Complex Diseases

Tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the 'limma' method <doi:10.1093/nar/gkv007>, interaction testing between sex and disease, pathway enrichment with 'clusterProfiler' <doi:10.1089/omi.2011.0118>, and gene regulatory network (GRN) construction and analysis using 'igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.

Version: 0.1.1

Depends: R (≥ 3.6)

Imports: limma, igraph, edgeR, Seurat, SeuratObject, clusterProfiler, org.Hs.eg.db, ReactomePA, data.table, ggplot2, tidyr, grid, ggraph, dplyr, ggrepel, scales, Rcpp, methods

LinkingTo: Rcpp

Suggests: R.utils, DT, gridExtra, knitr, htmltools, kableExtra, rmarkdown, stringr

Published: 2025年11月13日

DOI: 10.32614/CRAN.package.XYomics

Author: Enrico Glaab [aut, cre], Sophie Le Bars [aut], Mohamed Soudy [aut], Murodzhon Akhmedov [cph]

Maintainer: Enrico Glaab <enrico.glaab at uni.lu>

License: MIT + file LICENSE

NeedsCompilation: yes

Materials: README

CRAN checks: XYomics results

Documentation:

Reference manual: XYomics.html , XYomics.pdf

Vignettes: Bulk RNA-Seq Example (source, R code)
Single Cell Example (source, R code)

Downloads:

Package source: XYomics_0.1.1.tar.gz

Windows binaries: r-devel: XYomics_0.1.1.zip, r-release: XYomics_0.1.1.zip, r-oldrel: XYomics_0.1.1.zip

macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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