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Here is the code which causes this bug:
 proxy_handler = urllib2.ProxyHandler({'https': proxy})
 opener = urllib2.build_opener(proxy_handler)
 f = opener.open(url+'?'+params)
Here are the traceback information:
Traceback (most recent call last):
 File "proxy.py", line 65, in <module>
 main()
 File "proxy.py", line 62, in main
 print proxy_manager.get_proxy()
 File "proxy.py", line 45, in get_proxy
 make_request(TEST_URL, proxy=one["proxy_server"])
 File "proxy.py", line 27, in make_request
 f = opener.open(url+'?'+params)
 File "/usr/lib/python2.7/urllib2.py", line 400, in open
 response = self._open(req, data)
 File "/usr/lib/python2.7/urllib2.py", line 418, in _open
 '_open', req)
 File "/usr/lib/python2.7/urllib2.py", line 378, in _call_chain
 result = func(*args)
 File "/usr/lib/python2.7/urllib2.py", line 1215, in https_open
 return self.do_open(httplib.HTTPSConnection, req)
 File "/usr/lib/python2.7/urllib2.py", line 1174, in do_open
 h.request(req.get_method(), req.get_selector(), req.data, headers)
 File "/usr/lib/python2.7/httplib.py", line 958, in request
 self._send_request(method, url, body, headers)
 File "/usr/lib/python2.7/httplib.py", line 992, in _send_request
 self.endheaders(body)
 File "/usr/lib/python2.7/httplib.py", line 954, in endheaders
 self._send_output(message_body)
 File "/usr/lib/python2.7/httplib.py", line 814, in _send_output
 self.send(msg)
 File "/usr/lib/python2.7/httplib.py", line 776, in send
 self.connect()
 File "/usr/lib/python2.7/httplib.py", line 1160, in connect
 self._tunnel()
 File "/usr/lib/python2.7/httplib.py", line 748, in _tunnel
 line = response.fp.readline(_MAXLINE + 1)
TypeError: readline() takes exactly 1 argument (2 given)

Have a look at the ProxyHandler example in the Examples here - http://docs.python.org/library/urllib2.html#examples
Also, construct the full url properly with urlencoded data as params.
Your report does not give any details of problem.

Well, I do have encoded the params, that is not the problem.
Also these code did work for most of the time, I don't know why this bug happen so I don't know any details about the problem. Sorry about that.

What is proxy? Perhaps it does not implement readline correctly.